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Coagulation Impact
- Reduced plasminogen activator inhibitor (PAI-1) and von Willebrand
factor if dosage is 2+g/day with 800 IU of Vitamin E. Change not seen with
less.
- "Tissue plasminogen activator antigen levels were inversely related to
Vitamin C levels. Von Willebrand factor levels were slightly higher with
vitamin C,"
- The administration of ascorbic acid (1g/day) to healthy adults did not
significantly influence the levels of serum cholesterol, plasminogen
activator activity, plasminogen, fibrinogen, FR-antigen, partial
thromboplastin time, platelet adhesiveness, a-1-antitrypsin or
a-2-macroglobulin over the 3-month period of study."
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