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Sulfa drugs or Sulfonamides (like Bactrim) are felt to be inappropriate
antibiotics because they are ineffective against Cell Wall Deficient
organisms (CWD) that are common with CFS.
- ""As would be predicted by the lack of a cell wall, none of the beta
lactams are effective in vitro or in vivo against M pneumoniae and neither
are the sulfonamides or trimethoprim. "
Long Term Impacts
- may exacerbate lupus
often co-current with CFS
- Decreases or interferes with B-Vitamins
- thyroid malignancy
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency (hemolytic anemia
may occur in G6PD-deficient patients
- Hepatic function impairment
- Porphyria (sulfonamides may precipitate an acute attack of porphyria)
-
often co-current with CFS
Reference
- Long list of drug interactions
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