Statins
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Statins (3-hydroxy-3-methylglutaryl coenyzme A reductase inhibitors or HMG-CoA) are cholesterol reducing drugs which has also been found to affect coagulation and is anti-inflammatory.  "Statins are also considered to have anti-inflammatory, immunomodulating and antioxidant properties."

Benefits

  • depressed blood clotting, leading to reduced rates of prothrombin activation, FVa generation, fibrinogen cleavage, FXIII activation, and an increased rate of FVa inactivation.
  • pro-fibrinolytic/antithrombotic effects
  • an additional therapeutic tool in APS.
  • 'Calming' the lining of blood vessels (Hughes Syndrome)
  • Researchers have found that it helps reduces markers of microinflammation
  • Reduces inflammation in combination with angiotensin II inhibitors 

Risks

  • mild gastrointestinal symptoms ( < 3%)
  • Reduces CoQ10 levels
    • CoQ10 should be taken with Statins.

Source

  • MD

See

Note: Nystatin is NOT a coenyzme A reductase inhibitors.

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