Boron
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A recent post ( ) has called my attention to this mineral because it caused a rise of body temperature in CFS patients. Nutrients causing temporary or permanent normalization of the below average temperature seen in CFS/ME/GWS implies that there is a deficiency that is being corrected. In this case, it appears to moderate Vitamin D deficiencies and may be a significant adjunct for Vitamin D supplementation.

Possible Model:

  • Vitamin D deficiency --> increase consumption of boron
  • Change of Stomach pH (IBS, IGS) --> decrease availability of boron from food
    • Low boron levels --> decrease thyroid --> decrease body temperature

Boron

  • "Nutritional intakes of boron have been shown to lessen the adverse consequences of vitamin D deficiency "
  • "suggest that physiologic amounts of boron may help reduce the amount of insulin required to maintain plasma glucose."
  • Natural Sources:
    • Nuts and Dried Fruit:  2.2 lbs (1kg) --> 15-30mg
    • Wine: 2 liters --> 17 mg
  • May improve brain function -- "short periods of restricted boron intake may affect brain function and cognitive performance in healthy humans."
  • Need by the thyroid
  • "Boron's anti-inflammatory actions have been attributed to various mechanisms. These include suppression of serine proteases released by inflammation-activated white blood cells, inhibition of leukotriene synthesis, reduction of reactive oxygen species generated during neutrophil's respiratory burst, and suppression of T-cell activity and antibody concentrations. "

Risks

  • Boron is a trace mineral. Trace minerals can result in toxicity if too much is taken. It is essential to inform your MD if you are supplementing Boron, and to have periodic testing.
    • "The oral toxicity of boron is relatively low and it has been estimated that safe population mean intakes are <13 mg/day and that individuals are at risk of toxicity when intakes exceed 100 mg/day"
    • Tolerable Intake is estimated to be 0.4mg/KilogramKeep below 0.1mg/Kilogram for safety.
      • 110lb person (50 kg)--> 5mg
  • May mask Vitamin D deficiency. Make sure that you are taking at least 1200 IU/day of Vitamin D with it.

Reference:

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