|
 Acetylsalicylic acid or aspirn or ASA is the active ingredient of salicin
from  white willow bark (Salix alba) which has been synthetically created.
If you are doing any anticoagulants (herbs or prescription), please check with
your MD before using aspirin.
 EARLY in
my recovery taking 650mg (2 @ 325mg) of Aspirin with every meal for 10 days (maximum
dosage cited on the bottle) produced a major jump of energy about day 6.
I took it in the hope that it would impact coagulation, and ascribed the
energy to reduce coagulation alone -- in hind sight, it may also have worked
against infections.
Benefits
- Antibiotic effect on some infections associated with CFIDS
"Aspirin, its metabolite salicylic acid, and 2 other unrelated NF- > kB
inhibitors showed a strong concentration-dependent inhibitory effect on
chlamydial growth, indicated by the reduction of bacterial inclusions
and the titer of infectious progeny."
"The presented results show that aspirin at concentrations as low as
1024 mol/L markedly decreased chlamydial growth. These findings may be of
pharmacological relevance in vivo, inasmuch as serum concentrations of
10-4 to 10-5
mol/L are commonly achieved by therapeutic doses of aspirin in
humans."[full
text of article]
- anti-platelet activity [anticoagulant]
- protect against glutamate neurotoxicity. Aspirin protects cells
against ... inflammatory responses and neurodegeneration.
- "Its main physiological effect is inhibiting prostanoid synthesis.
the high clinical effectiveness of aspirin as an anti-inflammatory,
antipyretic, and analgesic drug. Aspirin shows a variety of
pharmacological activities, including:
- reduction of ATP storage pools,
- increased extracellular adenosine,
- lowered inducible nitric oxide synthase activity,
- modulation of mitogen-activated protein kinases, and
- the expression of a plethora of genes induced under conditions of
cell stress via the regulation of transcription factor NFkappaB
activity"
- Reduces or prevents the side-effects of niacin
- "In brain tissue subjected to hypoxia, ASA reduced oxidative stress and
iNOS activity (all increased by hypoxia), but only when used at higher
concentrations."
Risks
- Vitamin E potentiates the antiplatelet effect.
- Contains salicylates.
Some people are sensitive to
salicylates. For one
person's experience see
- anaphyllactic reaction
- risk of bleeding peptic ulcer
- used with caution, if at all, in somebody prone to
heartburn or
indigestion
- Not for use for those under 12 years of age (Reyes Syndrome Risk )
- Risk increase with H. pylori infection
NOTE: H. pylori can cause APS/coagulation and thus CFIDS.
Suggestion:
- If you have had no problems with aspirin, you may wish to try the above
experiment on your self. Some people who have tried it report feeling a bit
sick on the first few days (? herx ?). Check the current labeling on the
aspirin bottle and keep to the recommendation on maximum dosage.
- 0.5mg /kg(2.2lbs) is cited in
some studies for long term use.
- dosages > 100 mg/day have moderate risk of stomach problems
(especially if alcohol is consumed)
- Never exceed a dose of 1g (3 tablets) 4 times a day (4g daily
total) except on doctor's advice
- enteric coated tablets should be avoided because of the risk on
very poor absorption seen in some populations.
CFIDS people history of mal-absorption may be an important factor.
Reference:
Source
- Your local grocery store or pharmacy.
See
| |
Home
Original 2001 WebSite as PDF for download
|
