Lupus anticoagulant
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Lupus anticoagulant or Antiphospholipid Syndrome .

• Recognized as a disease in the 1970-80's
• Inherited or acquired. Seen with following drugs
1. Chlorpromazine
2. Procainamide
3. Fansidar
4. Phenothiazines

Symptoms

• Migraine headaches, transient ischemic attacks, or Guillain-Barre syndrome, skin appears mottled
• postpartum syndrome, which occurs 2-10 weeks after delivery and consists of fevers, dyspnea, pleuritic chest pain, pulmonary infiltrates, pleural effusions, cardiomyopathy, and arrhythmias

Treatment

• Heparin
• Warfarin

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