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Hughes Syndrome Testing
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The following tests are used to exclude Hughes Syndrome (and variants) as being the cause of CFS. All tests must be negative (there are many variants of Hughes Syndrome).

Immune System Activation of Coagulation Panel

For detection of "sticky blood" there are several tests. The usual US-CFS test is the ISAC Panel from Hemex laboratories (http://www.hemex.com)

Anticardiolipin Antibodies

This is a cheap test, but it requires two positive tests 6 months apart for a positive result.. It is suggested as a possible pre-ISAC panel test to justify the ISAC expense. (Note: a negative results does not imply a negative ISAC panel)

Lupus Anticoagulant

The name does not imply Lupus -- rather an antibody that is also seen with Lupus. Moderate number of positive results.

Wasserman Reaction

This is a very old syphilis test, a positive test does not imply syphilis, rather one form of Hughes Syndrome. Least amount of positive results.

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