The following risks are believed to exist from doing the
MarshallProtocol.com for persons
with Chronic Fatigue Syndrome, Lyme, Gulf War Illness / Sickness [GWI / GWS],
Fibromyalgia [FM], Irritable Bowel Disease [IBS IBD], Irritable Gut
Syndrome [IGS] . This list is based on literature found on the National
Institute of Health web site compared to an individual doing the
FWIW protocol for mal-absorption
illnesses such as those listed above. A person doing
the MarshallProtocol.com may not have any of them occurring (just like George
Burns had no illnesses associated with tobacco after almost 90 years of
- Major risk of Addison Syndrome (5%-25% of CFS that complete the
- Increased risk (
300%) of Heart Attack
- Increased risk (100+%) of Cancer (Breast, Colon and Prostate are well
- Increased risk (67+%) of Multiple Sclerosis
- Increased risk (400+%) of Diabetes
- Increased risk of Depression
- Increased risk (500+%) of Osteoarthritis and Osteoporosis
- Increased risk of nephrotic syndrome, schizophrenia and severe bipolar
- Increased risk of Hyperparathyroidism
- Increased risk of Crohn Disease and Sjogren's syndrome
- Increased risk of Rheumatoid Arthritis
- Increased risk of Systemic Lupus Erythematosus
- May cause fetal and neonatal morbidity and death
- Risk of Angioedema
Questions from a MPer and answers...
Trevor Marshall on Risks:
A report of an investigator on Trevor Marshall
- we are not responisbile for content]
Dr Cheney, MD, writes:
"I'm concerned that an ARB (Angiotensin Receptor Blocker) is being
used in CFIDS patients [via MarshallProtocol.com] without an awareness of its
effect on "Q."
Big issue [with MarshallProtocol.com]! If you block AT1 with an ARB [like
Benicar], down will go your Aldosterone, and down will go your blood volume, and
you could be in a heap of trouble [i.e. Addison Syndrome]. ARBs that bind to AT1
will constrict blood volume [which is unhealthy with PWCs].
I'm also concerned that the other receptor [AT2] is being ignored. No one knows
what it does. Not even Merck! I suspect that it has an immune effect. An ARB
like Benicar selectively binds very tightly to AT1, resulting in a two—to
three-fold increase of Angiotensin II, which then binds to the wide-open AT2
receptor. And who knows what kind of immune responses that is setting off. This
is just speculation, but I am concerned [over the safe use of Benicar for CFS].
"I don't believe that you can block a regulatory pathway [with Benicar],.....
you[MarshallProtocol.com] have no idea what that thing is doing and then hope
that down the road everything will be rosy."
What Medical Studies says about Vitamin D
"neither increased exposure to sunlight nor increased oral intake of
vitamin D raised blood concentrations of 1,25(OH)2D " (3 studies
"as a person becomes vitamin D-deficient, there is an increase in the
concentration of parathyroid hormone (PTH), which
increases the renal
production of 1,25(OH)2D, the circulating concentrations of which
often become normal or even elevated
From: Vitamin D: importance in the prevention of cancers, type 1
diabetes, heart disease, and osteoporosis, American Journal of
Clinical Nutrition, Vol. 79, No. 3, 362-371, March 2004 The full text
is available at:
What should your vitamin 25D reading be?
"Your vitamin D level should
NEVER be below 32 ng/ml.
Any levels below 20 ng/ml are considered serious defiency states and will
increase your risk of breast and prostate cancer and autoimmune diseases like MS
and rheumatoid arthritis.
25-hydroxyvitamin D values are:
45-50 ng/ml or 115-128 nmol/l"
Dr Joseph Mercola, MD
Feb 23, 2002
The following table indicates the approximate supplementation is needed (over
a 6 month period) to reach these levels. After 6 months (or more often), retest
and adjustment is recommended.
Daily IUs of D
Based on [source]
14 nmol/l = 1371 IU
Lancet. 1989 Nov 18;2(8673):1176-8. Serum 25-hydroxyvitamin D and
colon cancer: eight-year prospective study.
"Risk of getting colon cancer decreased three-fold
in people with a serum 25-OHD concentration of 20
ng/ml or more."